It is a bit better since 5.3.0.1, but is still making the browser very slow. Why is all this needed in the first place? I don't want the enpass extension do do anything, ever, unless I invoke it in order to fill in passwords.
I have the same problems in Firefox also on Windows. For example the GitHub notifications page becomes almost unusable, to a degree that I had to entirely disable the plugin for now. If I remember correctly, the error there is also related to jetpack.