Using the latest browser extension on chrome, it is not possible to close tabs by using cmd+w.
Did not test other shortcuts. But disabling the extension helps - which is just for debugging.
Chrome: Version 102.0.5005.61
Enpass: 6.7.5
edit: please delete > just found this chrome://extensions/shortcuts (cmd+w was set to close enpass. which is hopefully not the default setting since its a native browser shortcud)