Brave Version 1.20.103 Chromium: 88.0.4324.152 (Build officiel) (64 bits) It Work
https://community.brave.com/t/brave-version-1-21-73-chromium-89-0-4389-72-on-mac-breaks-enpass/212242/4
Turned off Brave Shields: Work but not a real solution
Workaround while waiting for a real solution
1 At start Brave, go setting turn off Brave Shields
2 Test Enpass, it work
3 And turn on Brave Shields, Brave+enpass work in this session.
If you restart Brave you must repeat step 1 to 3